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5.3.6 ROS enhances autophagy-lysosomal system-mediated muscle structural disruption The autophagy-lysosomal pathway (ALP) is an essential intracellular degradation system that maintains proteostasis by eliminating dysfunctional organelles and aggregated proteins

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Actin monomers are attached by TB-500, which also sequesters G-actin and promotes F-actin assembly