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Description

Direct stimulation of GLP-1R on cardiomyocytes increases cAMP and activates the PI3K/Akt pathway, thereby improving contractility and reducing apoptosis, which preserves left ventricular function and cardiac output ( , IL-6) and oxidative stress, further protecting the myocardium from inflammatory damage

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Hydroquinone inhibits tyrosinase through multiple simultaneous mechanisms it interferes with tyrosinase enzyme activity, disrupts melanosome formation, and has direct cytotoxic effects on hyperactive melanocytes

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