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In a randomised controlled trial published in the European Journal of Nutrition in 2014, Setria glutathione supplementation demonstrated significant increases in glutathione levels showing a 30% rise in whole blood, a 35% increase in red blood cells and a 260% increase in buccal cells

Because G6PD is an oligomeric globular protein, it is not surprising that many point mutations producing replacement of individual amino acids can further decrease the stability of G6PD

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