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In animal and preliminary human studies, BPC 157 showed the ability to: Accelerate regeneration of muscles, tendons, and ligaments Support brain and nervous system function Influence the lining of the gut Reduce inflammation markers Support sleep quality Enhance mood and mental clarity Promote blood vessel formation in injured tissues Support bone density and connective tissue integrity All of this from something born in the stomach

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A 2024 paper in Physiology & Behavior characterised that ipamorelin and the related GHSR-1a agonist anamorelin inhibited cisplatin-induced weight loss in ferrets, framing one route by which the GHSR-1a agonist class engages cachexia research (PMID 39043357)

Given this confirmation of positive phase 2 results, were raising our probability of approval to 60%, which raises our sales estimate to $8 billion by 2033