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Conversely, PYY can reduce leptin secretion (137)

To date, Phase 3 clinical trial data have also shown significant weight-loss outcomes, including up to 28.7% average body weight loss at 68 weeks in one obesity trial and 16.8% average weight loss at 40 weeks in adults with type 2 diabetes, with additional Phase 3 readouts still expected throughout 2026

These examples along with our findings here indicate that manipulating polyamine secretion from Candida species is a realistic target for therapeutic intervention of associated diseases

As promising as this all is, it doesn't mean that women who don't need a GLP-1 for other reasons should start taking it for breast cancer prevention, experts stress