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Erste Studien konnten zeigen, dass diese Kombination zu einem strkeren und nachhaltigeren Gewichtsverlust fhrt, vor allem der gefrchtete Rebound nach Ende der GLP-1-RA ist weniger stark (31)

SULT1A1 also takes part in transformation of hydroxymethyl polycyclic aromatic hydrocarbons, hydroxyderivatives of arylamines, allylic alcohols and heterocyclic amines to their reactive intermediates which are able to bind to nucleophilic structures such as DNA and consequently act as mutagens and carcinogens (Glatt et al., 2001)