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7 This is crucial as psoriasis is associated with an increased risk of cardiovascular events 8 and a patient may be taking medications that are metabolised by CYP/P-glycoprotein mechanisms

Similar findings in epidermal keratinocytes indicate that active Vitamin D analogues reduce NF-B DNA-binding activity, accompanied by IB upregulation and partial inhibition of subunit translocationsupporting the presence of a subunit-translocationindependent suppression mechanism in skin cells [207, 216]

If serious safety issues emerged, trials would be halted immediately (which hasnt happened)

95% confidence interval (CI), N = 16], with median BMI of 43.85 [37.358.79