Its therapeutic effects stem from GLP-1 receptor activation, which enhances insulin secretion, suppresses glucagon release, delays gastric emptying, and acts on the hypothalamus to reduce appetite and increase satiety [2]
Oral prednisone is strategically employed for HS patients in three ways: As Rescue during severe flares Bridge to biologics or surgery High dose 80mg daily for 3 days THEN taper by 10mg every 2-3 days (Total time on prednisone is 2-3 weeks) As Brakes to preemptively mitigate flares Can keep patients out of the ED 20-40mg daily for 3 days As maintenance treatment for severe HS in conjunction with other therapies For patients who have maximized other therapies, are unable to tolerate other therapies, or have a steroid-responsive comorbidity (e.g., Keratitis, PG) Prednisone 5-10mg daily Make sure to monitor calcium/vitamin D, blood sugar, and blood pressure and to obtain DEXA scans with long-term use of steroids Dr
In individuals with PCOS , insulin resistance and excess weight can interfere with ovulation , making it difficult to conceive
Without adequate nutrition, your body starts breaking down lean muscle tissue for fuel, which slows your metabolism and makes keeping weight off harder long-term
