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Author contributions XG was the chief investigator in charge of this trial program
TB-4: cell migration Full-length thymosin beta-4 (43 amino acids) moves repair cells (fibroblasts) into position and helps coordinate their movement through tissue (G-actin sequestration). It biases healing toward functional tissue over rope-like scarring (Ac-SDKP anti-fibrotic signaling) and calms blood-vessel cells, which shows up as less redness. GLOW uses the full-length parent, not the shorter TB-500 fragment
doi: 10.3390/jcm10163755, 217
Variability in hematoma location, patient selection, dosing regimen, and administration routes likely account for these discrepancies (Fig
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