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Why Did the FDA End Broad Compounding of Semaglutide and Tirzepatide

Patients should inform their physician if they have: Personal history of any cancer, including colorectal cancer or polyps Family history of colorectal cancer, especially in first-degree relatives Inflammatory bowel disease (Crohn's disease or ulcerative colitis) Genetic syndromes associated with increased cancer risk (Lynch syndrome, familial adenomatous polyposis) Previous radiation therapy to the abdomen or pelvis These factors affect baseline colorectal cancer risk independent of medication use

Even so, Zepbound patients are continuing to sue Eli Lilly and other GLP-1 manufacturers after they developed unexpected blindness, gastroparesis, and other side effects

In clinical trials (STEP programme), Wegovy has been shown to produce significant weight reduction, with patients without diabetes losing an average of 15% of their body weight over 68 weeks, though results vary by population