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Abbreviations BMI: body mass index ESG: endoscopic sleeve gastroplasty EWL: excess weight loss FDA: food and drug administration GLP-1: glucagon like peptide 1 IGB: intragastric balloon LRYGB: laparoscopic roux-en-y gastric bypass LSG: laparoscopic sleeve gastrectomy POSE: primary obesity surgery endoluminal TBE: transcatheter bariatric embolization TRL: triglyceride rich lipoproteins Declarations Acknowledgement None