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Side effects include nausea, diarrhea, and vomitingsimilar to the injectable formulation of semaglutide

In a clinical study conducted over twelve months, patients who used semaglutide injections lost an average of 1520% of their body weight over a year, compared to the minimal weight loss results achieved by patients in control groups following diet and exercise plans

If weight loss stalls despite correct dosing, troubleshooting tips for tirzepatide plateaus can help identify the issue

These include people with active cancer (any type), people who are pregnant or planning pregnancy, anyone with a known allergy to tesamorelin or mannitol (an inactive ingredient), and people with major problems of the hypothalamus or pituitary gland (the brain area that controls hormone release)