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Storage and Handling Reconstituted Retatrutide should be refrigerated at 2 to 8 degrees Celsius (roughly 36 to 46 degrees Fahrenheit)

IGF-DES Receptor Binding Specificity Competitive binding and receptor cross-linking experiments confirmed that both IGF-1 and des-(1-3)IGF-1 bind exclusively to the type 1 IGF receptor in L6 myoblasts, rat vascular smooth-muscle cells, and human lung fibroblasts with des-(1-3)IGF-1 demonstrating greater apparent potency in these assays, attributable to its low affinity for the competing 38 kDa IGFBP rather than differences in intrinsic receptor affinity

doi: 10.1038/s41416-021-01566-9 31 WangXLuSHeCWangCWangLPiaoMet al