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Inactive Ang I is then converted into Angiotensin II (Ang II) via the cleavage of two amino acids from the C-terminal by ACE1 at the endothelium

Alcoholism: Clinical and Experimental Research 34 , 251261, doi: 10.1111/j.1530-0277.2009.01088.x (2010)

Not surprisingly because of its stability, hydrophobic character, and small size, D-Nle- Tyr-ile-NH-(CH 2 )5-CONH 2 was predicted to be orally bioavailable