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It can make the scale fluctuate by 2-5 pounds on any given day due to retained food and water, but this is not true weight gain

Several regions of the brain express GLP-1Rs, including the ARC, PVN, and subfornical organ (SFO), and signals from GLP-1 are transmitted through the vagus nerve or converge on the NTS and area postrema (AP)

Reasonable candidates are patients already engaged in a supervised weight-loss programme with diet and activity in place, who understand it is adjunctive

This finding is clinically meaningful because it suggests that the risk may accumulate over time. Given that many individuals use these medications chronically, whether for blood sugar control or for weight loss, the long-term ocular safety of GLP-1 RAs requires further investigation, he continued