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An international study combining single-cell genomics, spatial transcriptomics and artificial intelligence has identified large-scale changes in three-dimensional genome organisation in Alzheimers-affected brain cells, establishing chromatin architecture as a previously overlooked component of the diseases molecular pathology and a potential framework for future therapeutic targeting
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These data suggest that autistic children of this age are particularly vulnerable to ASD-related factors such as energy deficits and oxidative stress
Intraoperative intraluminal injection of N-acetylcysteine allowing treatment of distal intestinal obstruction syndrome without the need for enterotomy
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