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4 Conclusion The pathogenesis of tissue damage induced by ionizing radiation is rooted in oxidative stress cascades triggered by the burst of free radicals, which include DNA double-strand breaks, mitochondrial dysfunction, and hyperactivation of inflammatory signaling pathways

Grip strength, as an example, has widely been adopted as a singular indicator of overall strength and low grip strength is a predictor of all-cause mortality.[1] While it is unknown what level of protein supplementation is needed for cessation of muscle catabolism, new evidence suggests we do not know the upper limit of protein metabolism [11] suggesting that current recommendations of protein consumption are too low, especially in populations that have additional protein needs

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In addition, its effects on microvascular and macrovascular complications are not known