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According to Medical News Today, people typically lose about 15% of their body weight on semaglutide, but without adequate protein and resistance training, a significant portion of that loss comes from muscle rather than fat alone

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Understanding obesity But while these are the general trends, responses to GLP-1 drugs can vary considerably on an individual level

The preclinical safety information for Wegovy adds: In developmental toxicity studies in rabbits and cynomolgus monkeys, increased pregnancy loss and slightly increased incidence of foetal abnormalities were observed at clinically relevant exposures. While the company is now carrying out trials to explore whether such drugs are safe for pregnant women, at present it advises that semaglutide should not be used during pregnancy as it is not known if it may affect an unborn child