does semaglutide affect libido Sex Drive, Erectile Dysfunction, and GLP-1 Side Effects Are Sexual Side Effects Emerging

10.1016/j.ejphar.2011.05.038 50 IlicS.DrmicD.ZarkovicK.KolencD.CoricM.BrcicL.et al (2010)

While GLP-2 does influence glucose metabolism to some extent, its principal role lies in promoting intestinal mucosal growth and maintaining mucosal stability [18]

A companion phase III trial reported a -10.9% reduction in visceral adipose tissue (a 21 cm decrease) in the tesamorelin group compared with -0.6% in the placebo group over the six-month efficacy phase, alongside significant improvements in trunk fat, waist circumference, and waist-hip ratio, with the authors concluding that tesamorelin reduces visceral fat by approximately 18% and improves body-image distress in HIV-infected patients with central fat accumulation, without significant side effects or disruption of glucose control

10.1126/sciadv.adt7981 193 XiaoZ.WangY.ChenY.JinL.ShiY.LiuC.et al (2025)