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IL-33-stimulated HMC-1.2 showed a reduction of IL-31 by about 70% in response to luteolin due to a possible inhibition of the IL-31/IL-33 axis

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The increase in circulating homocysteine related to impaired homocysteine metabolism may favor the accretion of a pro-oxidant environment by increasing concentrations of free radicals, by maintaining metal ions in their reduced state suitable for the Fenton reaction, and by changing the redox status of intra- and extracellular thiol groups and, hence, the intracellular redox potential (Mansoor et al, 1993a

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