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If nausea persists beyond 10 to 14 days at a new dose level, extend your stay at that dose for an additional 2 to 4 weeks before attempting escalation again

Glutathione is the most important intracellular antioxidant, and it is an essential cofactor for NOS (NO synthase)

S.HoJ.-Y.et al

In addition, we did not find a significant non-linear relationship between dose (g/day) (coefficients = 8.54, p = 0.054) and changes in HOMA-IR, although there was a significant non-linear relationship between duration of the intervention (coefficients = 0.22, p = 0.015) and changes in HOMA-IR