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(2025) further demonstrated in animal studies that IPA supplementation inhibited the NLR family pyrin domain containing 3(NLRP3) inflammasome via AhR activation, ameliorating dehydroepiandrosterone (DHEA)-induced PCOS phenotypes in mice, including restored ovarian morphology, improved insulin sensitivity, and normalized hormone levels (88)

Epidemiology 22 , 476485 (2011)

Some studies suggest that spironolactone combined with rosiglitazone may be more effective than Metformin in reducing excess hair growth, based on Ferriman-Gallwey hirsutism scores

Allocation of patients was assigned by simple randomization with stratification according to baseline levels of HbA 1c (greater or lower/equal to 7%)