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Evitar dosis muy altas superiores a tres gramos diarios de forma prolongada sin consideracin apropiada, ya que pueden asociarse con efectos no deseados como olor corporal caracterstico a pescado debido a la conversin de carnitina no absorbida por bacterias intestinales en trimetilamina, y no necesariamente proporcionan beneficios adicionales significativos comparados con dosis moderadas