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Standard vitamin C (ascorbic acid) can sometimes cause digestive discomfort because of its acidity, and some people find standard glutathione capsules difficult to tolerate

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Besides, disruption of MTR reaction leads to insufficient supply of methionine and S-adenosylmethionine (SAM), which is essential for the myelination of myelin sheath, phospholipids and neurotransmitter synthesis, for maintaining brain and nervous system function.51 Furthermore, high levels of homocysteine due to vitamin B 12 deficiency are associated with an increased risk of atherosclerotic vascular disease, and this in turn may increase the risk of cognitive impairment or dementia

These differences do not mean that one reference is necessarily wrong