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Ceramide generation was a critical component of Fas receptor-induced eryptosis, whereas therapy with natural organosulfur compounds inhibited the apoptotic death of erythrocytes by antagonizing oxidative stress and the Gardos channel that led to suppression of ceramide-initiated Fas aggregation in lipid rafts of these erythrocytes

Uridine engages PCBP1 as a direct target to restrain ferroptosis and maintain mitochondrial function of oocytes from aged mice To define protein effectors of uridine in aged ovaries, we performed LiP-SMap on ovarian lysates incubated with vehicle or uridine (Fig

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Vidmar GoljaMmidAKaras KuelikiNTronteljJGerakKMlinari-RaanI