This region-specific action is associated with its local stimulation of hormone-sensitive lipase and enhanced fatty acid oxidation, suggesting potential for site-selective metabolic modulation without systemic hormonal changes
We performed Cox proportional-hazards regression analysis with adjustment for traditional cardiovascular risk factors (age, sex, systolic blood pressure, presence or absence of diabetes mellitus, low-density and high-density lipoprotein cholesterol levels, triglyceride levels, and smoking status) and for log-transformed high-sensitivity C-reactive protein levels (both alone and with myeloperoxidase), the log-transformed estimated glomerular filtration rate, total leukocyte count, body-mass index, medication history, and angiographic extent of coronary artery disease
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Indocyanine green lymphangiography (ICG) demonstrated mild abnormal collateralization of lymphatic vessels and presence of lymphatic pumping and flow into the axilla