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Additionally, GLP-1 RAs modulate the hypothalamus (the region in the brain that controls appetite) to regulate hunger, slow gastric emptying, and regulate gut hormones such as leptin (a hormone that helps regulate body weight on a long-term basis)

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(CPS)" "R12.3: There is no evidence to show that stopping these medications even 1 week before the procedure will eliminate the risk of delayed gastric emptying, despite following the usual fasting timing for surgery

Gonadorelin was historically FDA-approved (e.g