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Discussing the Friday papers, Yale University School of Medicine Professor and JACC editor Harlan Krumholz said in a JACC interview, "I begin to think about the weight loss almost as a side effect, I mean these [drugs] are really promoting health." He added, "I was thinking mostly about cardiometabolic health but there may be many mechanisms by which [semaglutide] is making us healthier, and in some ways this is suggesting it's helping us to resist the adverse consequences of the pandemic." Krumholz nevertheless noted that further research into the impacts of semaglutide was required

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Energetics of 3-oxo-.DELTA.5-steroid Isomerase: Source of the Catalytic Power of the Enzyme