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Elevated serum zonulin levels, as well as bacterial dysbiosis and a leaky gut barrier, have been observed in patients with rheumatoid arthritis, while subclinical intestinal inflammation has been observed in patients with ankylosing spondylitis [74, 75]

Most researchers pick one day per week and inject at the same time for consistency

For anyone comparing the injectable format to other delivery methods, the honest takeaway is that format changes convenience and logistics rather than the underlying biology