They lack the systemic context necessary to recapitulate inter-organ crosstalk (e.g., hepatic regulation of cardiac copper) and are inherently static, making them unsuitable for modelling the gradual pathogenesis of chronic copper imbalances
Since AsA may donate a hydrogen atom to generate a relatively stable ascorbyl-free radical, it provides first line of defense against oxidative damage to proteins and lipid membranes
Bezerra AS, DIppolito G, Faintuch S, et al
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