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The EU has allocated 256 million euros to upgrade the Adriatic port infrastructures (Bodewig 2020), and national policies, such as Italys National Recovery and Resilience Plan (NRRP), have provided additional resources to accelerate their development (Twrdy and Zanne 2020

Pharmacokinetic analysis further revealed that the maximum plasma concentration (Cmax) of SIN in the microneedle group (0.74 0.13 mg/mL) was more than twice that of the hydrogel group (0.33 0.029 mg/mL)

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