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In addition, the exposure of cumulus-oocyte complex to a high lipid concentrations are known to have negative influences on oocyte maturation [68]

It is now clear that melanocytic nevi constitute benign neoplasms of cutaneous melanocytes, which frequently harbour oncogenic serine/threonine-protein kinase B-Raf (BRAF) or, less commonly, neuroblastoma ras viral oncogene homolog (NRAS) mutations

Furthermore, it has been reported that fatigue induced by progressive disease is often coupled with weight loss and anorexia [24]

In SURPASS-5[4], patients with type 2 diabetes achieved HbA1c reductions of -2.11% to -2.34% and weight loss from 5.4 kg at 5 mg to 10.5 kg at 15 mg over 40 weeks