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Transport and direct utilization of -glutamylcyst(e)ine for glutathione synthesis

Zepbound has not been studied in patients with a history of pancreatitis, or with severe gastrointestinal disease, including severe gastroparesis, and it is unknown if patients with a history of pancreatitis are at higher risk for developing pancreatitis on Zepbound

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The composition of PLs is controlled by lipid metabolism through the regulation of fatty acid supply(especially PUFAs) and remodeling of PLs synthesis, which in turn affects cell susceptibility to ferroptosis [13]