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However, caution should be exercised because although the administration of VEGF has a beneficial effect by reducing the formation of edema, the infusion of VEGF may also cause vascular leakage, which may consequently result in hemorrhagic transformation of ischemic lesions (Korn 2008)

Megaloblastic anemia is caused by the deficiency of: Vitamin B12 Folate Drugs, such as: Anticancer Antiretroviral Antiseizure Nonmegaloblastic macrocytic anemia: Non-megaloblastic anemia is not caused by an abnormality in the DNA synthesis, but it is caused due to metabolic abnormalities and liver diseases

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