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BPC-157 works primarily at the injury site for local tissue repair, while TB-500 has more systemic effects on muscle repair, inflammation, and flexibility

Since absorption of vitamin B12 depends on a protein called intrinsic factor produced in your stomach, some individuals may find it difficult to absorb the vitamin efficiently

doi:10.1111/aogs.12522

And then secondly, you're really hindered by the idea that you're studying that animal in an artificial environment and when you reduce the risk of a subset of death, a subset of causes of death which is effectively metabolic disease, you're often unable to measure what in my opinion is an underappreciated risk that comes on, which is, sort of, the more sudden and traumatic causes of death that we take for granted, especially in the case of caloric restriction