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Elevated blood TMAO levels cause an imbalance in cholesterol homeostasis which leads to influenced macrophages, which in turn causes foam cell development and atherosclerotic plaques [68, 69, 71]

Studies report that roughly 3057% of patients with chronic urticaria also have anti-thyroid antibodies

However, some emerging therapies for ALD have shown promising outcomes, including the inhibition of inflammatory pathways (e.g., anakinra), the promotion of liver regeneration (e.g., IL22 agonist, F-652), and restoration of the normal microbiota (e.g., probiotics and rifaximin)

This benefit becomes especially important for high-frequency training schedules or in-season athletic demands