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The integration of kinase (PKA, CDK5, GSK3) and small G-protein (IQGAP1) signalling pathways through CaMKK2, all of which have demonstrated links with human bipolar disorder, points to the possibility that bipolar disorder is a signalopathy that stems from defects in this signal transduction network, and potentially explains the clinical heterogeneity and polygenic nature of the condition

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[2] It is also added to many breakfast cereals through food fortification and is available in dietary supplement and pharmaceutical forms

But as more people use them, some are noticing unexpected emotional side effects, including low mood, anxiety, or even thoughts of self-harm