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Combined, the activities of CYP1A2 and CYP3A4 are comparable to that of CYP2E1, thus it is important to appreciate that these two enzymes can indeed contribute significantly to microsomal ethanol oxidation and thus, are likely to also contribute to the pathophysiology associated with hepatic ethanol oxidation

Vitamin B12 is watersoluble, meaning that excess amounts not needed by the body are usually filtered out through urine

Lithium is the drug that most qualifies to fulfil the term a mood stabiliser with a proven effect in mania, possibly bipolar depression [7], and prevention of manic as well as depressive episodes [35-38]