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GLP-1 may affect systemic energy metabolism by regulating adipocyte development, accelerating plasma clearance of glucose and triacylglycerol-derived fatty acids, improving insulin signaling, and stimulating thermogenesis in brown adipose tissue (BAT) [40-45]

Following recommended handling protocols supports both safety and optimal therapeutic outcomes throughout the treatment course

Document your family history with specific attention to medullary thyroid carcinoma in any first or second-degree relative, MEN 2 or related endocrine neoplasia syndromes, and any family member with pheochromocytoma (a tumor of the adrenal gland associated with MEN 2)

Both PCOS and obesity are also known to reduce fertility through similarly complex mechanisms