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The relationship between adipose tissue (AT) and glucose metabolism in PWS remains largely unknown, although several studies have observed indices of lower IR compared to controls (166, 183, 184)

These findings underscore the urgent need for targeted antioxidant therapies capable of quenching this systemic ROS burden and restoring metabolic homeostasis

CIBERSORT analysis To analyze immune cell proportions in the brainstem samples, the matrix of gene expression in TPM units was analyzed with CIBERSORT R script (version 1.02) 100 using the LM22 gene signature to deconvolute the proportions of 22 human immune cell types

For comparison, state of the art Hall sensors from traditional CMOS-compatible materials have sensitivity on the order of ~100 V/AT