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While mild increases are typical, severe or irregular heartbeats require immediate medical attention

For instance, a multicenter, placebo-controlled RCT could enroll several hundred heart failure patients on optimal therapy, randomizing them to add-on therapy with a purified TCM metabolite (at a standardized dose) versus placebo for 1 year

This was shown when a group of mice had improved symptoms of Metabolic Syndrome (MetS) including better regulation of glucose, triglycerides, and cholesterol levels after being given IGF-1.: Insulin growth factor 1 (IGF-1) has multiple effects on metabolism

Focus: Establishing digestive regularity