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In phase 3 clinical trials, participants using semaglutide (2.4 mg once weekly) showed 10-15% body weight reduction on average after 68 weeks

Highly invasive triple-negative MDA-MB-231 cells respond to 15 dyn/cm by increasing their migration velocity, whereas normal MCF-10 A epithelial cells and less aggressive triple-negative MDA-MB-468 breast cancer cells show only slight or no increase in motility under the same conditions, respectively [226]