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Table 2 Small molecule compounds targeting SLC7A11

More recently, a randomised controlled trial of lixisenatide in early Parkinson's disease (the LIXIPARK study) was published in the New England Journal of Medicine (2024)

Results Establishment of CRC Drug-Tolerant Persister Cell Models While modeling the response to the chemotherapeutic drug 5-FU in the CRC cell line HCT116, which has exquisite sensitivity, we observed that the vast majority of the cells were killed within 9 days of exposure to the drug at a concentration 10-fold higher than the IC 50 value ( Figure 1A )

NPA, rootlets treated with N-naphthyl phthalic acid solution (10 -5 M) for 24 h (from [31])) The role of IAA is proved by substantial change in the content of oxidized compounds under the action of N-naphthyl phthalic acid, an effective selective inhibitor of IAA transport