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What People Online Are Saying About Semaglutide vs Tirzepatide Beyond the trial literature, the Semaglutide vs Tirzepatide debate is discussed heavily in research and enthusiast communities online, including subreddits such as r/peptides, r/tirzepatide, r/semaglutide, and r/Mounjaro, along with various forums and review threads

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Nonetheless, it is reassuring that the reductions in HbA 1c and body weight from the multiple-dose trial are consistent with those results obtained in a substantially higher number of subjects in the phase II trial with oral semaglutide [10]