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Usually, the tumor has a benign, locally aggressive behavior, with recurrence of 10% to 15%, being eventually malignant in 6.97%, and acquiring metastatic capacity due to the proliferation of neuroblastic cells, with metastasis described in regional lymph nodes, liver, pleura, bone marrow, and pelvis

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The PBS only lists prophylactic B12 injections for maintaining B12 status in those with impaired gastric acidity and/or Intrinsic Factor