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doi: 10.1111/nmo.12184

Minerva Endocrinol (2015) 40(2):12943

As you age, egg quality declines primarily because of mitochondrial dysfunction and accumulated oxidative stress, which increase the risk of chromosomal abnormalities (aneuploidy) that are the leading cause of failed implantation, early miscarriage, and age-related infertility. Here's the part we find most reassuring: while no intervention can reverse reproductive ageing entirely, a growing body of evidence shows that targeted nutritional support, antioxidant supplementation, and specific lifestyle changes may genuinely help protect your remaining eggs from further oxidative damage and support the energy-intensive process of oocyte maturation. You're not powerless here, and the science backs that up

Mapping the structural determinants required for AAVrh.10 transport across the blood-brain barrier