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Compared to cytosolic NADK (cNADK), mitochondrial NADK (mNADK) has a distinctive feature that it can directly phosphorylate nicotinamide adenine dinucleotide (NADH) to generate NADPH to alleviate oxidative stress in mitochondria

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The SARS-CoV-2 isolate USA-WA1/2020 was deposited by the Centers for Disease Control and Prevention, and obtained through BEI Resources

Mitochondria serve as the primary intracellular source of ROS and emanate from electron leakage within the respiratory ETC