perioperative management of glp 1 agonists How should we approach patients on GLP-1 agonists? Check out this excellent editorial from Dr. Girish Joshi, "Clarifying the Guidelines and Decoding the Enigma: Strategies for Anesthetic Patients on Glucagon-Like Perioperative Use of GLP-1 Receptor

This might affect the viability of any ensuing embryo and cause problems with fertilization

In contrast, s.c

Taken together, these mechanistic and clinical threads support a model in PCOS whereby platelet activation and PMP release prime neutrophils for NETosis, and NETs provide a prothrombotic scaffold that recruits and activates additional platelets and coagulation factors, producing an escalating thrombo-inflammatory loop with potential consequences for ovarian microvasculature, endometrial receptivity, and long-term cardiovascular risk [77]

Selank's allosteric modulation enhances inhibitory tone only when and where endogenous GABA is being released, preserving the natural pattern of neural inhibition rather than globally dampening brain activity