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This phenotype is characterized by reduced maximal respiratory capacity, diminished basal oxygen consumption, and lower extracellular acidification ratesindicative of decreased lactate production and glycolytic activity ( Estrogens regulate the expression and activity of key enzymes in glycolysis, including hexokinase, phosphoglucoisomerase, phosphofructokinase, aldolase, glyceraldehyde-3-phosphate dehydrogenase, phosphoglycerate kinase, 6-phosphofructo-2-kinase, and fructose 2,6-bisphosphatase (Lizcano and Guzman, 2014)

Both drugs are meant to be used along with a reduced-calorie diet and regular physical activity

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Who Can Benefit from Glutathione Therapy