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Act 3: The Stacking Question What Longevity Experts Say About Combining Both The most sophisticated practitioners in the longevity space don't typically ask, "Should I use GLP-1 or BPC-157?" Instead, they ask, "When does each one belong in a protocol, and can they safely coexist?" The Complementary Logic Longevity-focused physicians and sports medicine practitioners have begun articulating a clear rationale for combining these compounds in specific patient profiles: The GLP-1 Layer: Addresses the metabolic side (reducing fat, improving insulin, lowering cardiovascular risk)

doi: 10.1128/mbio.03488-22 48 TongXXuJLianFYuXZhaoYXuLet al

HO-1 mediates catalytic breakdown of heme, a potent pro-oxidant and pro-inflammatory molecule 465

These endocrine disruptors may increase TSH and perpetuate the autoimmune attack on the thyroid